Analysis of Bivariate Survival Data using Shared Inverse Gaussian Frailty Model

نویسندگان

  • David D. Hanagal
  • Richa Sharma
چکیده

In this paper, we consider shared frailty model with inverse Gaussian distribution as frailty distribution and log-logistic distribution (LLD) as baseline distribution for bivariate survival times. We fit this model to three real life bivariate survival data sets. The problem of analyzing and estimating parameters of shared inverse Gaussian frailty is the interest of this paper and then compare the results with shared gamma frailty model under the same baseline for considered three data sets. Data are analyzed using Bayesian approach to the analysis of clustered survival data in which there is a dependence of failure time observations within the same group. The variance component estimation provides the estimated dispersion of the random effects. We carried out a test for frailty (or heterogeneity) using Bayes factor. Model comparison is made using information criteria and Bayes factor. We observed that the shared inverse Gaussian frailty model with LLD as baseline is the better fit for all three bivariate data sets.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Analysis of diabetic retinopathy data using shared inverse Gaussian frailty model

The dependence between individuals in a group is modeled by the group specific quantity, which can be interpreted as an unobserved covariates or “frailties” common to the individuals in the group and assumed to follow some distribution. We consider the shared frailty model in the frame work of parametric Cox proportional hazard model. The Cox regression model with the shared frailty factor allo...

متن کامل

Modeling heterogeneity for bivariate survival data by shared gamma frailty regression model

In the analysis of survival data with parametric models, it is well known that the Weibull model is not suitable for modeling survival data where the hazard rate is non-monotonic. For such cases, where hazard rates are bathtub-shaped or unimodal (or hump-shaped), log-logistic, lognormal, Birnbaun-Saunders, and inverse Gaussian models are used for the computational simplicity and popularity amon...

متن کامل

Comparison of Frailty Models for Acute Leukemia Data under Gompertz Baseline Distribution

Department of Statistics, University of Pune, Pune-411007, India. Email: david−[email protected]; richa−[email protected] Abstract In this paper, we consider two different shared frailty regression models under the assumption of Gompertz as baseline distribution. Mostly assumption of gamma distribution is considered for frailty distribution. To compare the results with gamma frailty model, ...

متن کامل

Correlated gamma frailty models for bivariate survival data

Frailty models are used in the survival analysis to account for the unobserved heterogeneity in individual risks to disease and death. To analyze the bivariate data on related survival times (e.g. matched pairs experiments, twin or family data), the shared frailty models were suggested. Shared frailty models are used despite their limitations. To overcome their disadvantages correlated frailty ...

متن کامل

Bayesian Inference in Marshall-Olkin Bivariate Exponential Shared Gamma Frailty Regression Model under Random Censoring

Department of Statistics, University of Pune, Pune-411007, India. Email: david−[email protected]; richa−[email protected] Abstract Many analysis in epidemiological and prognostic studies and in studies of event history data require methods that allow for unobserved covariates or “frailties”. We consider the shared frailty model in the frame work of parametric proportional hazard model. Ther...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013